临床儿科杂志 ›› 2016, Vol. 34 ›› Issue (4): 273-.doi: 10.3969 j.issn.1000-3606.2016.04.008

• 综合报道 • 上一篇    下一篇

单纯与共患对立违抗障碍的注意缺陷多动障碍儿童事件相关电位研究

冯婷婷, 张劲松, 王周烨, 帅澜, 夏卫萍   

  1. 上海交通大学医学院附属新华医院儿童与青少年保健科 临床心理科(上海 200092)
  • 收稿日期:2016-04-15 出版日期:2016-04-15 发布日期:2016-04-15
  • 通讯作者: 张劲松 E-mail:zhangjsq@yahoo.com
  • 基金资助:
    上海市科学技术委员会科研计划项目资助(No.10411966300)

Event related potentials study in children with attention deficit hyperactivity disorder or comorbid oppositional defiant disorder

FENG Tingting, ZHANG Jingsong, WANG Zhouye, SHUAI Lan, XIA Weiping   

  1. Department of Child and Adolescent Health, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Received:2016-04-15 Online:2016-04-15 Published:2016-04-15

摘要: 目的 探讨注意缺陷多动障碍(ADHD)儿童和ADHD共患对立违抗障碍(ODD)儿童与正常儿童相比对冲突的监测功能及解决能力的差异。方法 对15 例ADHD儿童、18 例ADHD共患ODD儿童和18 例正常儿童,进行事件相关电位(ERP)测试。结果 ERP显示,病例组(ADHD与ADHD共患ODD组)Go刺激的反应时高于正常对照组,正确率低于对照组,差异有统计学意义;Nogo 刺激的反应时和正确率与正常对照组的差异无统计学意义。病例组Go-N2,Nogo-N2 的潜伏期均大于对照组,差异有统计学意义,两病例组间无差别。病例组Nogo-P3b 的波幅较正常组小,两病例组之间无差别。结论 ADHD儿童对冲突的监测能力延迟;对冲突的决策处理能力减弱,尤其是在对冲突处理的后半程。

Abstract: Objective To investigate the differences of the ability to monitor and resolve the conflicts among children with attention deficit hyperactivity disorder (ADHD), ADHD comorbid oppositional defiant disorder (ODD), and normal children. Methods Event related potentials (ERP) were recorded in fifteen children with ADHD, 18 children with ADHD comorbid ODD, and 18 normal children. Results ERP results showed that the “Go” stimulation time were significantly longer and the correct rates were significantly lower in ADHD group and ADHD comorbid ODD group than those in control group. There were no differences in “Nogo” stimulation time and correct rate among ADHD group, ADHD comorbid ODD group and control group. Latency periods of Go-N2 and Nogo-N2 were significantly longer in ADHD group and ADHD comorbid ODD group than those in control group. However, there was no difference between ADHD group and ADHD comorbid ODD group. Amplitudes of Nogo-P3b were significantly smaller in ADHD group and ADHD comorbid ODD group than those in control group. There was no difference between ADHD group and ADHD comorbid ODD group. Conclusion In children with ADHD, the ability of conflict monitoring was delayed and the ability of conflict resolving was diminished, especially in the second half procession of conflict.